Nestlé Institute of Health Sciences to build up its capabilities in research on health and disease by integrating novel adult-derived stem cells products

The Nestlé Institute of Health Sciences SA (NIHS) has signed a long-term supply agreement with Cellular Dynamics International, Inc. (CDI), a company based in Madison, Wisconsin.

This agreement provides access to CDI’s cell products to support the Institute’s research programs aimed at developing targeted solutions for maintaining health and preventing disease. NIHS will employ CDI’s cell products to develop cellular models based on adult-derived induced pluripotent stem cells (iPSCs) to elucidate the molecular mechanisms that govern the progression to chronic diseases such as obesity and diabetes. These iPSC-derived cellular models are obtained from cells reprogrammed from a non-embryonic terminally differentiated cell type, which allows to avoid the controversial and ethical issues surrounding embryonic stem cells whilst serving as excellent models of human cellular and tissue physiology from healthy and disease states.

The cell products supplied by CDI include a variety of cell types that will benefit several areas of investigation at the Institute including Metabolic Health, Gastro-intestinal Health and Brain Health and will facilitate building the Institute’s platform for developing relevant cellular models of health and disease. NIHS has already begun working with and validating CDI’s human iPSC-derived cells, and has presented early results at the recent International Society for Stem Cell Research (ISSCR) at the 11th Annual Meeting and at the EASD Islet Study Group (ISG) Annual Meeting.

NIHS is the first biomedical research institute focused on the creation of science-based targeted nutritional solutions to maintain health, to prevent or manage chronic conditions, and to promote healthy aging. The goal of the Institute is to improve the understanding of the relationship between nutrition, life style, inherited factors and personal physiology, all of which can contribute to the susceptibility to chronic diseases. To achieve its goal, NIHS is employing state-of-the-art technologies and biological models to characterize health and disease with a holistic and integrated approach.

 

For scientific enquiries please contact:
Laura Camurri, Communication Manager, NIHS
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